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Monitoring of Leukemia Clones in B-cell Acute Lymphoblastic Leukemia at Diagnosis and During Treatment by Single-cell DNA Amplicon Sequencing

Acute lymphoblastic leukemia (ALL) is characterized by the presence of chromosomal changes, including numerical changes, translocations, and deletions, which are often associated with additional single-nucleotide mutations. In this study, we used single cell–targeted DNA sequencing to evaluate the c...

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Detalles Bibliográficos
Autores principales: Meyers, Sarah, Alberti-Servera, Llucia, Gielen, Olga, Erard, Margot, Swings, Toon, De Bie, Jolien, Michaux, Lucienne, Dewaele, Barbara, Boeckx, Nancy, Uyttebroeck, Anne, De Keersmaecker, Kim, Maertens, Johan, Segers, Heidi, Cools, Jan, Demeyer, Sofie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916209/
https://www.ncbi.nlm.nih.gov/pubmed/35291210
http://dx.doi.org/10.1097/HS9.0000000000000700