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Altered Differentiation and Inflammation Profiles Contribute to Enhanced Innate Responses in Severe COPD Epithelium to Rhinovirus Infection

BACKGROUND: Respiratory viral infections are closely associated with COPD exacerbations, hospitalisations, and significant morbidity and mortality. The consequences of the persisting inflammation and differentiation status in virus associated severe disease is not fully understood. The aim of this s...

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Detalles Bibliográficos
Autores principales: Guo-Parke, Hong, Linden, Dermot, Mousnier, Aurelie, Scott, Ian C., Killick, Helen, Borthwick, Lee A., Fisher, Andrew J., Weldon, Sinéad, Taggart, Clifford C., Kidney, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916560/
https://www.ncbi.nlm.nih.gov/pubmed/35280870
http://dx.doi.org/10.3389/fmed.2022.741989