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Single-molecule Taq DNA polymerase dynamics

Taq DNA polymerase functions at elevated temperatures with fast conformational dynamics—regimes previously inaccessible to mechanistic, single-molecule studies. Here, single-walled carbon nanotube transistors recorded the motions of Taq molecules processing matched or mismatched template–deoxynucleo...

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Detalles Bibliográficos
Autores principales: Turvey, Mackenzie W., Gabriel, Kristin N., Lee, Wonbae, Taulbee, Jeffrey J., Kim, Joshua K., Chen, Silu, Lau, Calvin J., Kattan, Rebecca E., Pham, Jenifer T., Majumdar, Sudipta, Garcia, Davil, Weiss, Gregory A., Collins, Philip G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916733/
https://www.ncbi.nlm.nih.gov/pubmed/35275726
http://dx.doi.org/10.1126/sciadv.abl3522