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Single-molecule Taq DNA polymerase dynamics
Taq DNA polymerase functions at elevated temperatures with fast conformational dynamics—regimes previously inaccessible to mechanistic, single-molecule studies. Here, single-walled carbon nanotube transistors recorded the motions of Taq molecules processing matched or mismatched template–deoxynucleo...
Autores principales: | Turvey, Mackenzie W., Gabriel, Kristin N., Lee, Wonbae, Taulbee, Jeffrey J., Kim, Joshua K., Chen, Silu, Lau, Calvin J., Kattan, Rebecca E., Pham, Jenifer T., Majumdar, Sudipta, Garcia, Davil, Weiss, Gregory A., Collins, Philip G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916733/ https://www.ncbi.nlm.nih.gov/pubmed/35275726 http://dx.doi.org/10.1126/sciadv.abl3522 |
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