Structural basis for HCMV Pentamer receptor recognition and antibody neutralization

Human cytomegalovirus (HCMV) represents the viral leading cause of congenital birth defects and uses the gH/gL/UL128-130-131A complex (Pentamer) to enter different cell types, including epithelial and endothelial cells. Upon infection, Pentamer elicits the most potent neutralizing response against H...

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Detalles Bibliográficos
Autores principales: Kschonsak, Marc, Johnson, Matthew C., Schelling, Rachel, Green, Evan M., Rougé, Lionel, Ho, Hoangdung, Patel, Nidhi, Kilic, Cem, Kraft, Edward, Arthur, Christopher P., Rohou, Alexis L., Comps-Agrar, Laetitia, Martinez-Martin, Nadia, Perez, Laurent, Payandeh, Jian, Ciferri, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916737/
https://www.ncbi.nlm.nih.gov/pubmed/35275719
http://dx.doi.org/10.1126/sciadv.abm2536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916737/
https://www.ncbi.nlm.nih.gov/pubmed/35275719
http://dx.doi.org/10.1126/sciadv.abm2536

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