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Signature-scoring methods developed for bulk samples are not adequate for cancer single-cell RNA sequencing data
Quantifying the activity of gene expression signatures is common in analyses of single-cell RNA sequencing data. Methods originally developed for bulk samples are often used for this purpose without accounting for contextual differences between bulk and single-cell data. More broadly, few attempts h...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916770/ https://www.ncbi.nlm.nih.gov/pubmed/35212622 http://dx.doi.org/10.7554/eLife.71994 |