5,8-Dihydroxy-4 ′, 7-dimethoxyflavone Attenuates TNF-α-Induced Expression of Vascular Cell Adhesion Molecule-1 through EGFR/PKCα/PI3K/Akt/Sp1-Dependent Induction of Heme Oxygenase-1 in Human Cardiac Fibroblasts

Recently, we found that 5,8-dihydroxy-4′,7-dimethoxyflavone (DDF) upregulated the expression of heme oxygenase (HO)-1 via p38 mitogen-activated protein kinase/nuclear factor-erythroid factor 2-related factor 2 (MAPK/Nrf2) pathway in human cardiac fibroblasts (HCFs). However, the alternative processe...

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Detalles Bibliográficos
Autores principales: Yang, Chien-Chung, Hsiao, Li-Der, Shih, Ya-Fang, Lin, Hsin-Hui, Yang, Chuen-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916851/
https://www.ncbi.nlm.nih.gov/pubmed/35281466
http://dx.doi.org/10.1155/2022/1372958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916851/
https://www.ncbi.nlm.nih.gov/pubmed/35281466
http://dx.doi.org/10.1155/2022/1372958

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