A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution

Bulk-tissue DNA methylomes represent an average over many different cell types, hampering our understanding of cell-type-specific contributions to disease development. As single-cell methylomics is not scalable to large cohorts of individuals, cost-effective computational solutions are needed, yet c...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Tianyu, Liu, Jacklyn, Beck, Stephan, Pan, Sun, Capper, David, Lechner, Matt, Thirlwell, Chrissie, Breeze, Charles E., Teschendorff, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916958/
https://www.ncbi.nlm.nih.gov/pubmed/35277705
http://dx.doi.org/10.1038/s41592-022-01412-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916958/
https://www.ncbi.nlm.nih.gov/pubmed/35277705
http://dx.doi.org/10.1038/s41592-022-01412-7

Ejemplares similares