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A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution

Bulk-tissue DNA methylomes represent an average over many different cell types, hampering our understanding of cell-type-specific contributions to disease development. As single-cell methylomics is not scalable to large cohorts of individuals, cost-effective computational solutions are needed, yet c...

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Detalles Bibliográficos
Autores principales:	Zhu, Tianyu, Liu, Jacklyn, Beck, Stephan, Pan, Sun, Capper, David, Lechner, Matt, Thirlwell, Chrissie, Breeze, Charles E., Teschendorff, Andrew E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916958/ https://www.ncbi.nlm.nih.gov/pubmed/35277705 http://dx.doi.org/10.1038/s41592-022-01412-7

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