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The Janus kinase inhibitor (baricitinib) suppresses the rheumatoid arthritis active marker gliostatin/thymidine phosphorylase in human fibroblast-like synoviocytes

Gliostatin/thymidine phosphorylase (GLS/TP) is known to have angiogenic and arthritogenic activities in the pathogenesis of rheumatoid arthritis (RA). The novel oral Janus kinase (JAK) inhibitor baricitinib has demonstrated high efficacy in RA. However, the effect of baricitinib on fibroblast-like s...

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Detalles Bibliográficos
Autores principales: Joyo, Yuji, Kawaguchi, Yohei, Yonezu, Hiroki, Senda, Hiroya, Yasuma, Sanshiro, Shiraga, Hiroo, Nozaki, Masahiro, Aoyama, Mineyoshi, Asai, Kiyofumi, Murakami, Hideki, Waguri-Nagaya, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917024/
https://www.ncbi.nlm.nih.gov/pubmed/35014010
http://dx.doi.org/10.1007/s12026-022-09261-4