CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT

Type 3 Secretion System (T3SS) is a highly conserved virulence structure that plays an essential role in the pathogenesis of many Gram-negative pathogenic bacteria, including Pseudomonas aeruginosa. Exotoxin T (ExoT) is the only T3SS effector protein that is expressed in all T3SS-expressing P. aerug...

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Detalles Bibliográficos
Autores principales: Mohamed, Mohamed F., Gupta, Kajal, Goldufsky, Josef W., Roy, Ruchi, Callaghan, Lauren T., Wetzel, Dawn M., Kuzel, Timothy M., Reiser, Jochen, Shafikhani, Sasha H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917168/
https://www.ncbi.nlm.nih.gov/pubmed/35277504
http://dx.doi.org/10.1038/s41467-022-28967-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917168/
https://www.ncbi.nlm.nih.gov/pubmed/35277504
http://dx.doi.org/10.1038/s41467-022-28967-5

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