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CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT
Type 3 Secretion System (T3SS) is a highly conserved virulence structure that plays an essential role in the pathogenesis of many Gram-negative pathogenic bacteria, including Pseudomonas aeruginosa. Exotoxin T (ExoT) is the only T3SS effector protein that is expressed in all T3SS-expressing P. aerug...
Autores principales: | Mohamed, Mohamed F., Gupta, Kajal, Goldufsky, Josef W., Roy, Ruchi, Callaghan, Lauren T., Wetzel, Dawn M., Kuzel, Timothy M., Reiser, Jochen, Shafikhani, Sasha H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917168/ https://www.ncbi.nlm.nih.gov/pubmed/35277504 http://dx.doi.org/10.1038/s41467-022-28967-5 |
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