Cargando…
Coincidence of cholinergic pauses, dopaminergic activation and depolarisation of spiny projection neurons drives synaptic plasticity in the striatum
Dopamine-dependent long-term plasticity is believed to be a cellular mechanism underlying reinforcement learning. In response to reward and reward-predicting cues, phasic dopamine activity potentiates the efficacy of corticostriatal synapses on spiny projection neurons (SPNs). Since phasic dopamine...
Autores principales: | Reynolds, John N. J., Avvisati, Riccardo, Dodson, Paul D., Fisher, Simon D., Oswald, Manfred J., Wickens, Jeffery R., Zhang, Yan-Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917208/ https://www.ncbi.nlm.nih.gov/pubmed/35277506 http://dx.doi.org/10.1038/s41467-022-28950-0 |
Ejemplares similares
-
Cholinergic interneurons in the rat striatum modulate substitution of habits
por: Aoki, Sho, et al.
Publicado: (2018) -
Pauses in cholinergic interneuron firing exert an inhibitory control on striatal output in vivo
por: Zucca, Stefano, et al.
Publicado: (2018) -
Coordination of rapid cholinergic and dopaminergic signaling in striatum during spontaneous movement
por: Howe, Mark, et al.
Publicado: (2019) -
Depolarisation requirements
por: Jowett, J
Publicado: (1991) -
The Effect of Serotonin Receptor 5-HT1B on Lateral Inhibition between Spiny Projection Neurons in the Mouse Striatum
por: Pommer, Stefan, et al.
Publicado: (2021)