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Comprehensive 3D epigenomic maps define limbal stem/progenitor cell function and identity

The insights into how genome topology couples with epigenetic states to govern the function and identity of the corneal epithelium are poorly understood. Here, we generate a high-resolution Hi-C interaction map of human limbal stem/progenitor cells (LSCs) and show that chromatin multi-hierarchical o...

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Detalles Bibliográficos
Autores principales: Li, Mingsen, Huang, Huaxing, Wang, Bofeng, Jiang, Shaoshuai, Guo, Huizhen, Zhu, Liqiong, Wu, Siqi, Liu, Jiafeng, Wang, Li, Lan, Xihong, Zhang, Wang, Zhu, Jin, Li, Fuxi, Tan, Jieying, Mao, Zhen, Liu, Chunqiao, Ji, Jianping, Ding, Junjun, Zhang, Kang, Yuan, Jin, Liu, Yizhi, Ouyang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917218/
https://www.ncbi.nlm.nih.gov/pubmed/35277509
http://dx.doi.org/10.1038/s41467-022-28966-6