The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation

Yeast Cadmium Factor 1 (Ycf1) sequesters heavy metals and glutathione into the vacuole to counter cell stress. Ycf1 belongs to the ATP binding cassette C-subfamily (ABCC) of transporters, many of which are regulated by phosphorylation on intrinsically-disordered domains. The regulatory mechanism of...

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Detalles Bibliográficos
Autores principales: Khandelwal, Nitesh Kumar, Millan, Cinthia R., Zangari, Samantha I., Avila, Samantha, Williams, Dewight, Thaker, Tarjani M., Tomasiak, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917219/
https://www.ncbi.nlm.nih.gov/pubmed/35277487
http://dx.doi.org/10.1038/s41467-022-28811-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917219/
https://www.ncbi.nlm.nih.gov/pubmed/35277487
http://dx.doi.org/10.1038/s41467-022-28811-w

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