Loss of the Bardet-Biedl protein Bbs1 alters photoreceptor outer segment protein and lipid composition

Primary cilia are key sensory organelles whose dysfunction leads to ciliopathy disorders such as Bardet-Biedl syndrome (BBS). Retinal degeneration is common in ciliopathies, since the outer segments (OSs) of photoreceptors are highly specialized primary cilia. BBS1, encoded by the most commonly muta...

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Detalles Bibliográficos
Autores principales: Masek, Markus, Etard, Christelle, Hofmann, Claudia, Hülsmeier, Andreas J., Zang, Jingjing, Takamiya, Masanari, Gesemann, Matthias, Neuhauss, Stephan C. F., Hornemann, Thorsten, Strähle, Uwe, Bachmann-Gagescu, Ruxandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917222/
https://www.ncbi.nlm.nih.gov/pubmed/35277505
http://dx.doi.org/10.1038/s41467-022-28982-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917222/
https://www.ncbi.nlm.nih.gov/pubmed/35277505
http://dx.doi.org/10.1038/s41467-022-28982-6

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