Controlled human malaria infections by mosquito bites induce more severe clinical symptoms than asexual blood-stage challenge infections

BACKGROUND: Fever and inflammation are a hallmark of clinical Plasmodium falciparum (Pf) malaria induced by circulating asexual parasites. Although clinical manifestations of inflammation are associated with parasite density, this relationship is influenced by a complex network of immune-modulating...

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Detalles Bibliográficos
Autores principales: Alkema, Manon, Yap, X. Zen, de Jong, Gerdie M., Reuling, Isaie J., de Mast, Quirijn, van Crevel, Reinout, Ockenhouse, Christian F., Collins, Katharine A., Bousema, Teun, McCall, Matthew B.B., Sauerwein, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917304/
https://www.ncbi.nlm.nih.gov/pubmed/35278741
http://dx.doi.org/10.1016/j.ebiom.2022.103919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917304/
https://www.ncbi.nlm.nih.gov/pubmed/35278741
http://dx.doi.org/10.1016/j.ebiom.2022.103919

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