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The APC/C targets the Cep152–Cep63 complex at the centrosome to regulate mitotic spindle assembly

The control of protein abundance is a fundamental regulatory mechanism during mitosis. The anaphase-promoting complex/cyclosome (APC/C) is the main protein ubiquitin ligase responsible for the temporal regulation of mitotic progression. It has been proposed that the APC/C might fulfil other function...

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Detalles Bibliográficos
Autores principales: Tischer, Thomas, Yang, Jing, Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917351/
https://www.ncbi.nlm.nih.gov/pubmed/34878135
http://dx.doi.org/10.1242/jcs.259273