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Pthlha and mechanical force control early patterning of growth zones in the zebrafish craniofacial skeleton

Secreted signals in patterning systems often induce repressive signals that shape their distributions in space and time. In developing growth plates (GPs) of endochondral long bones, Parathyroid hormone-like hormone (Pthlh) inhibits Indian hedgehog (Ihh) to form a negative-feedback loop that control...

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Detalles Bibliográficos
Autores principales: Hoyle, Diego J., Dranow, Daniel B., Schilling, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917414/
https://www.ncbi.nlm.nih.gov/pubmed/34919126
http://dx.doi.org/10.1242/dev.199826