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Pthlha and mechanical force control early patterning of growth zones in the zebrafish craniofacial skeleton
Secreted signals in patterning systems often induce repressive signals that shape their distributions in space and time. In developing growth plates (GPs) of endochondral long bones, Parathyroid hormone-like hormone (Pthlh) inhibits Indian hedgehog (Ihh) to form a negative-feedback loop that control...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917414/ https://www.ncbi.nlm.nih.gov/pubmed/34919126 http://dx.doi.org/10.1242/dev.199826 |