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IL7Rα, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells

Tissue-resident lymphoid cells (TLCs) span the spectrum of innate-to-adaptive immune function. Unlike traditional, circulating lymphocytes that are continuously generated from hematopoietic stem cells (HSCs), many TLCs are of fetal origin and poorly generated from adult HSCs. Here, we sought to furt...

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Detalles Bibliográficos
Autores principales: Worthington, Atesh K., Cool, Taylor, Poscablo, Donna M., Hussaini, Adeel, Beaudin, Anna E., Forsberg, E. Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917444/
https://www.ncbi.nlm.nih.gov/pubmed/35072209
http://dx.doi.org/10.1242/dev.200139