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Improvement of the anticancer efficacy of PD-1/PD-L1 blockade via combination therapy and PD-L1 regulation

Immune checkpoint molecules are promising anticancer targets, among which therapeutic antibodies targeting the PD-1/PD-L1 pathway have been widely applied to cancer treatment in clinical practice and have great potential. However, this treatment is greatly limited by its low response rates in certai...

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Detalles Bibliográficos
Autores principales: Wu, Mengling, Huang, Qianrui, Xie, Yao, Wu, Xuyi, Ma, Hongbo, Zhang, Yiwen, Xia, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917703/
https://www.ncbi.nlm.nih.gov/pubmed/35279217
http://dx.doi.org/10.1186/s13045-022-01242-2