Deep learning-driven prediction of drug mechanism of action from large-scale chemical-genetic interaction profiles

MOTIVATION: Chemical–genetic interaction profiling is a genetic approach that quantifies the susceptibility of a set of mutants depleted in specific gene product(s) to a set of chemical compounds. With the recent advances in artificial intelligence, chemical–genetic interaction profiles (CGIPs) can...

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Detalles Bibliográficos
Autores principales: Liu, Chengyou, Hogan, Andrew M., Sturm, Hunter, Khan, Mohd Wasif, Islam, Md. Mohaiminul, Rahman, A. S. M. Zisanur, Davis, Rebecca, Cardona, Silvia T., Hu, Pingzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917716/
https://www.ncbi.nlm.nih.gov/pubmed/35279211
http://dx.doi.org/10.1186/s13321-022-00596-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917716/
https://www.ncbi.nlm.nih.gov/pubmed/35279211
http://dx.doi.org/10.1186/s13321-022-00596-6

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