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Pedigree investigation, clinical characteristics, and prognosis analysis of haematological disease patients with germline TET2 mutation

BACKGROUND: Increasing germline gene mutations have been discovered in haematological malignancies with the development of next-generation sequencing (NGS), which is critical for proper clinical management and long-term follow-up of affected individuals. Tet methylcytosine dioxygenase 2 (TET2) is on...

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Detalles Bibliográficos
Autores principales: Wu, Xia, Deng, Jili, Zhang, Nanchen, Liu, Xiaoyan, Zheng, Xue, Yan, Tianyou, Ye, Wu, Gong, Yuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917718/
https://www.ncbi.nlm.nih.gov/pubmed/35279121
http://dx.doi.org/10.1186/s12885-022-09347-0