Cargando…

Pedigree investigation, clinical characteristics, and prognosis analysis of haematological disease patients with germline TET2 mutation

BACKGROUND: Increasing germline gene mutations have been discovered in haematological malignancies with the development of next-generation sequencing (NGS), which is critical for proper clinical management and long-term follow-up of affected individuals. Tet methylcytosine dioxygenase 2 (TET2) is on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Xia, Deng, Jili, Zhang, Nanchen, Liu, Xiaoyan, Zheng, Xue, Yan, Tianyou, Ye, Wu, Gong, Yuping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917718/ https://www.ncbi.nlm.nih.gov/pubmed/35279121 http://dx.doi.org/10.1186/s12885-022-09347-0

Ejemplares similares

Clinical characteristics and registry-validated extended pedigrees of germline TP53 mutation carriers in Denmark
por: Stoltze, Ulrik, et al.
Publicado: (2018)

The m(6)A RNA methyltransferase METTL3/METTL14 promotes leukemogenesis through the mdm2/p53 pathway in acute myeloid leukemia
por: Sang, Lina, et al.
Publicado: (2022)

Vitamin C boosts DNA demethylation in TET2 germline mutation carriers
por: Taira, Aurora, et al.
Publicado: (2023)

Comparison of monoclonal antibodies targeting CD38, SLAMF7 and PD-1/PD-L1 in combination with Bortezomib/Immunomodulators plus dexamethasone/prednisone for the treatment of multiple myeloma: an indirect-comparison Meta-analysis of randomised controlled trials
por: Ye, Wu, et al.
Publicado: (2021)

The Mutationathon highlights the importance of reaching standardization in estimates of pedigree-based germline mutation rates
por: Bergeron, Lucie A, et al.
Publicado: (2022)

Prognostic significance of KMT2A-PTD in patients with acute myeloid leukaemia: a systematic review and meta-analysis
por: Ye, Wu, et al.
Publicado: (2023)

Novel germline ERCC5 mutations identified in a xeroderma pigmentosum complementation group G pedigree
por: Wang, Tao, et al.
Publicado: (2015)

Clinicopathological characteristics and postoperative prognosis of patients with nuclear pedigree of esophageal squamous cell carcinoma
por: Wei, Meng Xia, et al.
Publicado: (2023)

Pedigree based DNA sequencing pipeline for germline genomes of cancer families
por: Försti, Asta, et al.
Publicado: (2016)

Novel germline mutation in lung cancer pedigrees establishes BCAR1 as a human cancer susceptibility gene: a case report
por: Zhu, Kuikui, et al.
Publicado: (2022)

FTL mutation in a Chinese pedigree with neuroferritinopathy
por: Ni, Wang, et al.
Publicado: (2016)

Germline variation networks in the PI3K/AKT pathway corresponding to familial high-incidence lung cancer pedigrees
por: Lin, Huan, et al.
Publicado: (2020)

Targeted Mutations Produce Divergent Characteristics in Pedigreed Sake Yeast Strains
por: Klinkaewboonwong, Norapat, et al.
Publicado: (2023)

Positive Germline Selection in Pedigrees With Multiple Endocrine Neoplasia Type 2 Carrying V804M Mutation in the RET Gene
por: Peddareddygari, Leema Reddy, et al.
Publicado: (2016)

Bottleneck and selection in the germline and maternal age influence transmission of mitochondrial DNA in human pedigrees
por: Zaidi, Arslan A., et al.
Publicado: (2019)

Identification of Novel Causal FBN1 Mutations in Pedigrees of Marfan Syndrome
por: Wang, Yueli, et al.
Publicado: (2018)

MRI characteristics due to gene mutations in a Chinese pedigree with Lafora disease
por: Sun, Yueqian, et al.
Publicado: (2023)

Novel missense mutation in PTPN22 in a Chinese pedigree with Hashimoto’s thyroiditis
por: Gong, Licheng, et al.
Publicado: (2018)

Functional polymorphisms of the TET1 gene increase the risk of neuroblastoma in Chinese children
por: Chang, Jiaming, et al.
Publicado: (2023)

Haematological characteristics and risk factors in the classification and prognosis evaluation of COVID-19: a retrospective cohort study
por: Liao, Danying, et al.
Publicado: (2020)

TET2 mutations and clonal dynamics
por: Kishtagari, Ashwin, et al.
Publicado: (2019)

The Potential Equivalents of TET2 Mutations
por: Pasca, Sergiu, et al.
Publicado: (2021)

Reduced Expression of TET1, TET2, TET3 and TDG mRNAs Are Associated with Poor Prognosis of Patients with Early Breast Cancer
por: Yang, Liu, et al.
Publicado: (2015)

Prognosis of patients with haematological malignancies admitted to the ICU
por: Geerse, DA, et al.
Publicado: (2008)

Routine haematological parameters in COVID-19 prognosis
por: Pereyra, David, et al.
Publicado: (2020)

Mutation detection and prenatal diagnosis of XLHED pedigree
por: Lin, Yao, et al.
Publicado: (2017)

Prognostic value of SRSF2 mutations in patients with de novo myelodysplastic syndromes: A meta-analysis
por: Zheng, Xue, et al.
Publicado: (2017)

Infrequent occurrence of TET1, TET3, and ASXL2 mutations in myelodysplastic/myeloproliferative neoplasms
por: Lasho, Terra L., et al.
Publicado: (2018)

A large Chinese pedigree of multiple endocrine neoplasia type 2A with a novel C634Y/D707E germline mutation in RET exon 11
por: Lu, Fanqian, et al.
Publicado: (2017)

Sirolimus is effective in autoimmune lymphoproliferative syndrome-type III: A pedigree case report with homozygous variation PRKCD
por: Gu, Hao, et al.
Publicado: (2021)

Clinical characteristics and genetic analysis of gene mutations in a Chinese pedigree with Peutz‐Jeghers syndrome
por: Qiu, Yudian, et al.
Publicado: (2019)

Characteristics of Germline and Non-germline Retinoblastomas
por: Ghassemi, Fariba, et al.
Publicado: (2014)

Pedigree analysis of the EGFR p.V1010M germline mutation in a family with a family history of non-small-cell lung cancer
por: Li, Na, et al.
Publicado: (2022)

Effects of BRCA Germline Mutations on Triple-Negative Breast Cancer Prognosis
por: Pogoda, Katarzyna, et al.
Publicado: (2020)

The germline mutational landscape of genitourinary cancers and its indication for prognosis and risk
por: Yang, Yong, et al.
Publicado: (2022)

Strategic plan for management of COVID-19 in paediatric haematology and oncology departments
por: He, Yulei, et al.
Publicado: (2020)

Characteristics and Follow-Up of Organizing Pneumonia Associated with Haematological Malignancies
por: Zeng, Huihui, et al.
Publicado: (2022)

Simultaneous Homozygous Mutations in SLC12A3 and CLCNKB in an Inbred Chinese Pedigree
por: Mou, Lijun, et al.
Publicado: (2021)

Expression and prognosis analysis of TET family in acute myeloid leukemia
por: Zhang, Tingjuan, et al.
Publicado: (2020)

Characteristics and Follow-Up of 13 pedigrees with Gitelman syndrome
por: Zhong, F., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_h1d4d25u1ed7uvigvotuua0ce1