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Endothelial colony-forming cell-derived exosomal miR-21-5p regulates autophagic flux to promote vascular endothelial repair by inhibiting SIPL1A2 in atherosclerosis

BACKGROUND: Percutaneous transluminal coronary angioplasty (PTCA) represents an efficient therapeutic method for atherosclerosis but conveys a risk of causing restenosis. Endothelial colony-forming cell-derived exosomes (ECFC-exosomes) are important mediators during vascular repair. This study aimed...

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Detalles Bibliográficos
Autores principales: Ke, Xiao, Liao, Zhiyong, Luo, Xinlin, Chen, Jun-qiu, Deng, Ming, Huang, Yiteng, Wang, Zanxin, Wei, Minxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917727/
https://www.ncbi.nlm.nih.gov/pubmed/35279183
http://dx.doi.org/10.1186/s12964-022-00828-0