Adverse stem cell clones within a single patient’s tumor predict clinical outcome in AML patients

Acute myeloid leukemia (AML) patients suffer dismal prognosis upon treatment resistance. To study functional heterogeneity of resistance, we generated serially transplantable patient-derived xenograft (PDX) models from one patient with AML and twelve clones thereof, each derived from a single stem c...

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Detalles Bibliográficos
Autores principales: Zeller, Christina, Richter, Daniel, Jurinovic, Vindi, Valtierra-Gutiérrez, Ilse A., Jayavelu, Ashok Kumar, Mann, Matthias, Bagnoli, Johannes W., Hellmann, Ines, Herold, Tobias, Enard, Wolfgang, Vick, Binje, Jeremias, Irmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917742/
https://www.ncbi.nlm.nih.gov/pubmed/35279202
http://dx.doi.org/10.1186/s13045-022-01232-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917742/
https://www.ncbi.nlm.nih.gov/pubmed/35279202
http://dx.doi.org/10.1186/s13045-022-01232-4

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