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Recombinant human endostatin combined with radiotherapy promotes cardiomyocyte apoptosis in rats via TGFβ1/Smads/CTGF signaling pathway

PURPOSE: The aim of the present study was to investigate the efficacy of recombinant human endostatin (ES) (rh-ES) combined with radiation on rat cardiomyocyte apoptosis and the regulatory mechanism of transforming growth factor beta1 (TGF-β1)/Sma and Mad-related protein 3 (Smad3)/connective tissue...

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Detalles Bibliográficos
Autores principales: Ouyang, Weiwei, Fu, Shimei, Zhao, Xing, Su, Shengfa, Zhang, Jun, Luo, Daxian, Liu, Lina, Ding, Wenjin, Cao, Dongdong, Liu, Likun, He, Zhixu, Lu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917752/
https://www.ncbi.nlm.nih.gov/pubmed/35279096
http://dx.doi.org/10.1186/s12872-022-02499-8