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Clonidine for sedation in infants during therapeutic hypothermia with neonatal encephalopathy: pilot study

OBJECTIVE: To determine a safe dose of clonidine (CLON) to be used in infants with hypoxic ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). STUDY DESIGN: A pilot prospective study was performed to determine the effect of CLON on autonomic parameters, the pharmacokinetics (PK) o...

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Detalles Bibliográficos
Autores principales: Gauda, Estelle B, Chavez-Valdez, Raul, Northington, Frances J, Lee, Carlton KK, Rudek, Michelle A, Guglieri-Lopez, Beatriz, Ivaturi, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917970/
https://www.ncbi.nlm.nih.gov/pubmed/34531532
http://dx.doi.org/10.1038/s41372-021-01151-1