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Early Alzheimer's disease‐like reductions in gray matter and cognitive function with aging in nonhuman primates

INTRODUCTION: Age‐related neuropathology associated with sporadic Alzheimer's disease (AD) often develops well before the onset of symptoms. Given AD's long preclinical period, translational models are needed to identify early signatures of pathological decline. METHODS: Using structural m...

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Detalles Bibliográficos
Autores principales: Frye, Brett M., Craft, Suzanne, Register, Thomas C., Kim, Jeongchul, Whitlow, Christopher T., Barcus, Richard A., Lockhart, Samuel N., Sai, Kiran Kumar Solingapuram, Shively, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918111/
https://www.ncbi.nlm.nih.gov/pubmed/35310523
http://dx.doi.org/10.1002/trc2.12284