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Experimental investigation of a combinational iron chelating protoporphyrin IX prodrug for fluorescence detection and photodynamic therapy

Photodynamic therapy (PDT) is an oxygen-dependent, light-activated, and locally destructive drug treatment of cancer. Protoporphyrin IX (PpIX)-induced PDT exploits cancer cells’ own innate heme biosynthesis to hyper-accumulate the naturally fluorescent and photoactive precursor to heme, PpIX. This o...

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Detalles Bibliográficos
Autores principales: Magnussen, Anette, Reburn, Charlotte, Perry, Alexis, Wood, Mark, Curnow, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918167/
https://www.ncbi.nlm.nih.gov/pubmed/34218351
http://dx.doi.org/10.1007/s10103-021-03367-1