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S100A16 promotes acute kidney injury by activating HRD1-induced ubiquitination and degradation of GSK3β and CK1α

The pathogenesis of acute kidney injury (AKI) is associated with the activation of multiple signaling pathways, including Wnt/β-catenin signaling. However, the mechanism of Wnt/β-catenin pathway activation in renal interstitial fibroblasts during AKI is unclear. S100 calcium-binding protein A16 (S10...

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Detalles Bibliográficos
Autores principales: Sun, Yifei, Fan, Ya, Wang, Zheng, Li, Min, Su, Dongming, Liu, Yun, Liang, Xiubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918193/
https://www.ncbi.nlm.nih.gov/pubmed/35279748
http://dx.doi.org/10.1007/s00018-022-04213-5