Cargando…
S100A16 promotes acute kidney injury by activating HRD1-induced ubiquitination and degradation of GSK3β and CK1α
The pathogenesis of acute kidney injury (AKI) is associated with the activation of multiple signaling pathways, including Wnt/β-catenin signaling. However, the mechanism of Wnt/β-catenin pathway activation in renal interstitial fibroblasts during AKI is unclear. S100 calcium-binding protein A16 (S10...
Autores principales: | Sun, Yifei, Fan, Ya, Wang, Zheng, Li, Min, Su, Dongming, Liu, Yun, Liang, Xiubin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918193/ https://www.ncbi.nlm.nih.gov/pubmed/35279748 http://dx.doi.org/10.1007/s00018-022-04213-5 |
Ejemplares similares
-
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation
por: Huang, Yujie, et al.
Publicado: (2017) -
HRD1 sensitizes breast cancer cells to Tamoxifen by promoting S100A8 degradation
por: Wang, YanYang, et al.
Publicado: (2017) -
Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase
por: Rubenstein, Eric M., et al.
Publicado: (2012) -
Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression
por: Fan, Ya, et al.
Publicado: (2021) -
E3 Ubiquitin Ligase HRD1 Promotes Lung Tumorigenesis by Promoting Sirtuin 2 Ubiquitination and Degradation
por: Liu, Liu, et al.
Publicado: (2020)