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Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation

Fbxo45, a conserved F-box protein, comprises of an atypical SKP1, CUL1, F-box protein (SCF) ubiquitin ligase complex that promotes tumorigenesis and development. However, the biological function and molecular mechanisms of Fbxo45 involved in pancreatic carcinogenesis are ambiguous. We conducted seve...

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Detalles Bibliográficos
Autores principales: Wu, Linhui, Yu, Ke, Chen, Kai, Zhu, Xuelian, Yang, Zheng, Wang, Qi, Gao, Junjie, Wang, Yingying, Cao, Tong, Xu, Hui, Pan, Xueshan, Wang, Lixia, Xia, Jun, Li, Yuyun, Wang, Zhiwei Peter, Ma, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918322/
https://www.ncbi.nlm.nih.gov/pubmed/35279684
http://dx.doi.org/10.1038/s41419-022-04675-2