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Clock-modified mesenchymal stromal cells therapy rescues molecular circadian oscillation and age-related bone loss via miR142-3p/Bmal1/YAP signaling axis

Age-related bone loss and disease strongly affect the quality of life of the elderly population. Cellular circadian rhythms have been reported to regulate bone aging, and micro RNAs (miRNAs) play crucial posttranscriptional regulatory roles in the peripheral clock network. Proliferation capability,...

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Detalles Bibliográficos
Autores principales: Cha, Sa, Wang, Jiangyue, Lee, Sueng Min, Tan, Zhen, Zhao, Qing, Bai, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918353/
https://www.ncbi.nlm.nih.gov/pubmed/35279674
http://dx.doi.org/10.1038/s41420-022-00908-7