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Clock-modified mesenchymal stromal cells therapy rescues molecular circadian oscillation and age-related bone loss via miR142-3p/Bmal1/YAP signaling axis
Age-related bone loss and disease strongly affect the quality of life of the elderly population. Cellular circadian rhythms have been reported to regulate bone aging, and micro RNAs (miRNAs) play crucial posttranscriptional regulatory roles in the peripheral clock network. Proliferation capability,...
Autores principales: | Cha, Sa, Wang, Jiangyue, Lee, Sueng Min, Tan, Zhen, Zhao, Qing, Bai, Ding |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918353/ https://www.ncbi.nlm.nih.gov/pubmed/35279674 http://dx.doi.org/10.1038/s41420-022-00908-7 |
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