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N-terminome analyses underscore the prevalence of SPPL3-mediated intramembrane proteolysis among Golgi-resident enzymes and its role in Golgi enzyme secretion

Golgi membrane proteins such as glycosyltransferases and other glycan-modifying enzymes are key to glycosylation of proteins and lipids. Secretion of soluble Golgi enzymes that are released from their membrane anchor by endoprotease activity is a wide-spread yet largely unexplored phenomenon. The in...

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Detalles Bibliográficos
Autores principales: Hobohm, Laura, Koudelka, Tomas, Bahr, Fenja H., Truberg, Jule, Kapell, Sebastian, Schacht, Sarah-Sophie, Meisinger, Daniel, Mengel, Marion, Jochimsen, Alexander, Hofmann, Anna, Heintz, Lukas, Tholey, Andreas, Voss, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918473/
https://www.ncbi.nlm.nih.gov/pubmed/35279766
http://dx.doi.org/10.1007/s00018-022-04163-y