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Method Improving for Isolation and Characterization of Allergy-Inducing Polymer Impurities in Cefotaxime Sodium Medicines Available From Pharmaceutical Industry

Objective: To prepare and validate the chemical structure of the cefotaxime dimer and cefotaxime trimer impurities available from pharmaceutical industry. Methods: A polymer stock solution of cefotaxime sodium was obtained using a concentrated solution degradation method. The cefotaxime dimer and tr...

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Detalles Bibliográficos
Autores principales: Fu, Yanan, Li, Jin, Feng, Fang, Yin, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918496/
https://www.ncbi.nlm.nih.gov/pubmed/35295978
http://dx.doi.org/10.3389/fchem.2022.820730