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Exploring the Mechanism of Danshensu in the Treatment of Doxorubicin-Induced Cardiotoxicity Based on Network Pharmacology and Experimental Evaluation

BACKGROUND: Doxorubicin (DOX) is one of the most effective chemotherapeutic agents available; however, its use is limited by the risk of serious cardiotoxicity. Danshensu (DSS), an active ingredient in Salvia miltiorrhiza, has multiple cardioprotective effects, but the effect of DSS on DOX-induced c...

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Detalles Bibliográficos
Autores principales: Qi, Jia-ying, Yang, Ya-kun, Jiang, Chuan, Zhao, Yang, Wu, Yong-chao, Han, Xue, Jing, Xuan, Wu, Zhong-lin, Chu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918531/
https://www.ncbi.nlm.nih.gov/pubmed/35295262
http://dx.doi.org/10.3389/fcvm.2022.827975