Peptidomes and Structures Illustrate How SLA-I Micropolymorphism Influences the Preference of Binding Peptide Length

Polymorphisms can affect MHC-I binding peptide length preferences, but the mechanism remains unclear. Using a random peptide library combined with LC-MS/MS and de novo sequencing (RPLD-MS) technique, we found that two swine MHC-I molecules with high sequence homology, SLA-1*04:01 and SLA-1*13:01, ha...

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Detalles Bibliográficos
Autores principales: Wei, Xiaohui, Li, Shen, Wang, Suqiu, Feng, Guojiao, Xie, Xiaoli, Li, Zhuolin, Zhang, Nianzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918614/
https://www.ncbi.nlm.nih.gov/pubmed/35296092
http://dx.doi.org/10.3389/fimmu.2022.820881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918614/
https://www.ncbi.nlm.nih.gov/pubmed/35296092
http://dx.doi.org/10.3389/fimmu.2022.820881

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