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Antigen Reactivity and Clinical Significance of Autoantibodies Directed Against the Pyruvate Dehydrogenase Antigen Complex in Patients With Connective Tissue Disease

INTRODUCTION: Antimitochondrial antibodies (AMAs) are the hallmark of primary biliary cholangitis (PBC) but can be identified also in patients with connective tissue disease, namely, systemic sclerosis (SSc). Protein immunoprecipitation (IP) and IP-Western blot (WB) can be used to confirm AMA positi...

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Detalles Bibliográficos
Autores principales: Ceribelli, Angela, Isailovic, Natasa, Gorlino, Carolina, Assandri, Roberto, Vecellio, Matteo, De Santis, Maria, Satoh, Minoru, Selmi, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918651/
https://www.ncbi.nlm.nih.gov/pubmed/35296099
http://dx.doi.org/10.3389/fimmu.2022.822996