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Decoding the Role of Astrocytes in the Entorhinal Cortex in Alzheimer’s Disease Using High-Dimensional Single-Nucleus RNA Sequencing Data and Next-Generation Knowledge Discovery Methodologies: Focus on Drugs and Natural Product Remedies for Dementia

Introduction: Alzheimer’s disease (AD) is a major cause of the development of cognitive decline and dementia. AD and associated dementias (ADRD) are the major contributors to the enormous burden of morbidity and mortality worldwide. To date, there are no robust therapies to alleviate or cure this de...

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Detalles Bibliográficos
Autores principales: Pushparaj, Peter Natesan, Kalamegam, Gauthaman, Wali Sait, Khalid Hussain, Rasool, Mahmood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918735/
https://www.ncbi.nlm.nih.gov/pubmed/35295737
http://dx.doi.org/10.3389/fphar.2021.720170