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Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells

Insulin secretion in pancreatic β-cells is regulated by cortical complexes that are enriched at the sites of adhesion to extracellular matrix facing the vasculature. Many components of these complexes, including bassoon, RIM, ELKS and liprins, are shared with neuronal synapses. Here, we show that in...

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Detalles Bibliográficos
Autores principales: Noordstra, Ivar, van den Berg, Cyntha M., Boot, Fransje W. J., Katrukha, Eugene A., Yu, Ka Lou, Tas, Roderick P., Portegies, Sybren, Viergever, Bastiaan J., de Graaff, Esther, Hoogenraad, Casper C., de Koning, Eelco J. P., Carlotti, Françoise, Kapitein, Lukas C., Akhmanova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918791/
https://www.ncbi.nlm.nih.gov/pubmed/35006275
http://dx.doi.org/10.1242/jcs.259430