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Liquid Chromatography-Tandem Mass Spectrometry Analysis Demonstrates a Decrease in Porins and Increase in CMY-2 β-Lactamases in Escherichia coli Exposed to Increasing Concentrations of Meropenem

While Extended-Spectrum β-Lactamases (ESBL) and AmpC β-lactamases barely degrade carbapenem antibiotics, they are able to bind carbapenems and prevent them from interacting with penicillin-binding proteins, thereby inhibiting their activity. Further, it has been shown that Enterobacterales can becom...

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Detalles Bibliográficos
Autores principales: Foudraine, Dimard E., Aarents, Camiel N. M., Wattel, Agnes A., van Boxtel, Ria, Strepis, Nikolaos, ten Kate, Marian T., Verbon, Annelies, Luider, Theo M., Klaassen, Corné H. W., Hays, John, Dekker, Lennard J. M., Tommassen, Jan, Goessens, Wil H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918824/
https://www.ncbi.nlm.nih.gov/pubmed/35295306
http://dx.doi.org/10.3389/fmicb.2022.793738