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Single-treatment tumor ablation with photodynamic liposomal irinotecan sucrosulfate

Irinotecan (IRI) loaded actively into PEGylated liposomes via a sucrosulfate gradient has been approved recently to treat advanced pancreatic cancer. In this study, a similar liposomal composition was developed that includes a low mole fraction (1 mol.%) of porphyrin-phospholipid (PoP), a photosensi...

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Detalles Bibliográficos
Autores principales: Ghosh, Sanjana, Sun, Boyang, Jahagirdar, Dushyant, Luo, Dandan, Ortega, Joaquin, Straubinger, Robert M., Lovell, Jonathan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918863/
https://www.ncbi.nlm.nih.gov/pubmed/35290919
http://dx.doi.org/10.1016/j.tranon.2022.101390