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Single-treatment tumor ablation with photodynamic liposomal irinotecan sucrosulfate
Irinotecan (IRI) loaded actively into PEGylated liposomes via a sucrosulfate gradient has been approved recently to treat advanced pancreatic cancer. In this study, a similar liposomal composition was developed that includes a low mole fraction (1 mol.%) of porphyrin-phospholipid (PoP), a photosensi...
Autores principales: | Ghosh, Sanjana, Sun, Boyang, Jahagirdar, Dushyant, Luo, Dandan, Ortega, Joaquin, Straubinger, Robert M., Lovell, Jonathan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918863/ https://www.ncbi.nlm.nih.gov/pubmed/35290919 http://dx.doi.org/10.1016/j.tranon.2022.101390 |
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