Application of predictive models in boosting power of Alzheimer's disease clinical trials: A post hoc analysis of phase 3 solanezumab trials

BACKGROUND: The ideal participants for Alzheimer's disease (AD) clinical trials would show cognitive decline in the absence of treatment (i.e., placebo arm) and would also respond to the therapeutic intervention. OBJECTIVE: To investigate if predictive models can be an effective tool for identi...

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Detalles Bibliográficos
Autores principales: Ezzati, Ali, Davatzikos, Christos, Wolk, David A., Hall, Charles B., Habeck, Christian, Lipton, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919041/
https://www.ncbi.nlm.nih.gov/pubmed/35310531
http://dx.doi.org/10.1002/trc2.12223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919041/
https://www.ncbi.nlm.nih.gov/pubmed/35310531
http://dx.doi.org/10.1002/trc2.12223

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