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Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations
The cell stress‐responsive transcription factor p53 influences the expression of its target genes and subsequent cellular responses based in part on its dynamics (changes in level over time). The mechanisms decoding p53 dynamics into subsequent target mRNA and protein dynamics remain unclear. We sys...
Autores principales: | Jiménez, Alba, Lu, Dan, Kalocsay, Marian, Berberich, Matthew J, Balbi, Petra, Jambhekar, Ashwini, Lahav, Galit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919251/ https://www.ncbi.nlm.nih.gov/pubmed/35285572 http://dx.doi.org/10.15252/msb.202110588 |
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