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Effect of Preoperative Administration of Oral Melatonin on Pneumatic Tourniquet-Induced Ischemia-Reperfusion Injury in Orthopedic Surgery of Lower Extremities: A Randomized Clinical Trial

BACKGROUND: Ischemic reperfusion injury (IRI) causes cellular damage and dysfunction. The present study aimed to evaluate the effect of melatonin on pneumatic tourniquet-induced IRI in orthopedic surgery of the lower extremities. METHODS: A randomized clinical trial was conducted at Chamran Hospital...

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Detalles Bibliográficos
Autores principales: Jouybar, Reza, Khademi, Saeed, Razmjooie, Sima, Bagheri, Neda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919302/
https://www.ncbi.nlm.nih.gov/pubmed/35291433
http://dx.doi.org/10.30476/ijms.2021.86960.1701