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ADAD2 regulates heterochromatin in meiotic and post-meiotic male germ cells via translation of MDC1

Male germ cells establish a unique heterochromatin domain, the XY-body, early in meiosis. How this domain is maintained through the end of meiosis and into post-meiotic germ cell differentiation is poorly understood. ADAD2 is a late meiotic male germ cell-specific RNA-binding protein, loss of which...

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Detalles Bibliográficos
Autores principales: Chukrallah, Lauren G., Badrinath, Aditi, Vittor, Gabrielle G., Snyder, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919335/
https://www.ncbi.nlm.nih.gov/pubmed/35191498
http://dx.doi.org/10.1242/jcs.259196