Cargando…

Epithelial plasticity in COPD results in cellular unjamming due to an increase in polymerized actin

The airway epithelium is subjected to insults such as cigarette smoke (CS), a primary cause of chronic obstructive pulmonary disease (COPD) and serves as an excellent model to study cell plasticity. Here, we show that both CS-exposed and COPD-patient derived epithelia (CHBE) display quantitative evi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghosh, Baishakhi, Nishida, Kristine, Chandrala, Lakshmana, Mahmud, Saborny, Thapa, Shreeti, Swaby, Carter, Chen, Si, Khosla, Atulya Aman, Katz, Joseph, Sidhaye, Venkataramana K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919336/
https://www.ncbi.nlm.nih.gov/pubmed/35118497
http://dx.doi.org/10.1242/jcs.258513